Now, this is something that I should have done a long time ago, as I was missing it for the last 8 years or so, that I have Squeezebox music players. The original remote is pretty weak, and if you don’t have your SB on your desk, you’ll probably have to turn yourself around if you want to change the volume using the remote (if you can actually find it on your desk), of course, controlling it through the web interface is also an option, but I sometimes prefer hardware keys.
As you might know, there’s a Squeezebox Server CLI, so it’s obvious to use it. Then, there’s the possibility to assign a “shortcut key” to a shortcut in Windows. The missing part is the Windows version of Netcat, some shortcuts, and a small “parameter” file for each function.
Step by Step, for volume Control:
1. Download Netcat, extract it to a folder, that you want to use for the whole thing.
2. Create the parameter files, my volup.txt looks like this:
XX:XX:XX:XX:XX:XX mixer volume +1
exit
Be sure to add an extra line break, because otherwise, Netcat will stay open. Create config files for every function you want to use.
3. Create the shortcuts, my volume down shortcut looks like this:
C:\Windows\System32\cmd.exe /c "C:\Program Files (x86)\squeezevol\nc.exe" aese-02 9090 < volup.txt
4. Add a "shortcut key", like CTRL ALT +
Set it to run minimized.

It's working good and fast, I hope you enjoy it too.